Transition metal- and solvent-free anti-Markovnikov selective protoboration of alkenes with bis(pinacolato)diboron.
Org Biomol Chem
; 21(25): 5274-5280, 2023 Jun 28.
Article
em En
| MEDLINE
| ID: mdl-37309755
ABSTRACT
An efficient anti-Markovnikov selective transition metal- and solvent-free Lewis base-mediated protoboration of aromatic and aliphatic alkenes with bis(pinacolato)diboron (B2pin2) as the boron reagent is reported. This protocol is practical and demonstrates broad substrate scope and good functional-group tolerance on alkenes to give synthetically useful alkyl boronate esters in excellent yields under mild reaction conditions. The gram-scale reaction further highlighted the usefulness of this method.
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1
Base de dados:
MEDLINE
Tipo de estudo:
Guideline
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Índia