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Ni-Catalyzed Protecting Group Free Diphenic Acid Analog Synthesis.
Zhao, Bo-Wei; Yang, Liu; Long, Cheng-Yu; Li, Han-Lu; He, Yu-Ting; Wang, Xue-Qiang.
Afiliação
  • Zhao BW; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), the Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
  • Yang L; Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
  • Long CY; Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
  • Li HL; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), the Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
  • He YT; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), the Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
  • Wang XQ; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), the Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Org Lett ; 25(25): 4700-4704, 2023 06 30.
Article em En | MEDLINE | ID: mdl-37314939
ABSTRACT
Severe side effects and drug resistance are major drawbacks of Pt-based chemotherapy in clinical practice, leading to the search for new Pt-based drugs through the tuning of coordination ligands. Therefore, seeking appropriate ligands has attracted significant interest in this area. In this study, we report a Ni-catalyzed coupling strategy for the divergent synthesis of diphenic acid derivatives and the application of these newly prepared acids in Pt(II) agent synthesis.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Bifenilo Idioma: En Revista: Org Lett Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Bifenilo Idioma: En Revista: Org Lett Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China