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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Bayerl, Felix; Meiser, Philippa; Donakonda, Sainitin; Hirschberger, Anna; Lacher, Sebastian B; Pedde, Anna-Marie; Hermann, Chris D; Elewaut, Anais; Knolle, Moritz; Ramsauer, Lukas; Rudolph, Thomas J; Grassmann, Simon; Öllinger, Rupert; Kirchhammer, Nicole; Trefny, Marcel; Anton, Martina; Wohlleber, Dirk; Höchst, Bastian; Zaremba, Anne; Krüger, Achim; Rad, Roland; Obenauf, Anna C; Schadendorf, Dirk; Zippelius, Alfred; Buchholz, Veit R; Schraml, Barbara U; Böttcher, Jan P.
Afiliação
  • Bayerl F; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Meiser P; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Donakonda S; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany; German Center for Infection Research, Munich, Germany.
  • Hirschberger A; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Lacher SB; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Pedde AM; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Hermann CD; Institute of Experimental Oncology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Elewaut A; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
  • Knolle M; Institute for Artificial Intelligence in Medicine & Healthcare, School of Medicine, Technical University of Munich, Munich, Germany.
  • Ramsauer L; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Rudolph TJ; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Grassmann S; Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Munich, Germany.
  • Öllinger R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Munich, Germany.
  • Kirchhammer N; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.
  • Trefny M; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.
  • Anton M; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Wohlleber D; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Höchst B; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Zaremba A; Department for Dermatology, University Hospital Essen, Essen, Germany.
  • Krüger A; Institute of Experimental Oncology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Rad R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Munich, Germany.
  • Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.
  • Schadendorf D; Department for Dermatology, University Hospital Essen, Essen, Germany.
  • Zippelius A; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.
  • Buchholz VR; Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Munich, Germany.
  • Schraml BU; Walter-Brendel Center for Experimental Medicine, LMU Munich, Planegg-Martinsried, Germany; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, LMU Munich, Planegg-Martinsried, Germany.
  • Böttcher JP; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany. Electronic address: j.boettcher@tum.de.
Immunity ; 56(6): 1341-1358.e11, 2023 06 13.
Article em En | MEDLINE | ID: mdl-37315536
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dinoprostona / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dinoprostona / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha