Association of endothelial to mesenchymal transition and cellular senescence with fibrosis in skin biopsies of systemic sclerosis patients: a cross-sectional study.

Chiu, Yu-Hsiang; Spierings, Julia; van Laar, Jacob M; de Vries-Bouwstra, Jeska K; van Dijk, Marijke; Goldschmeding, Roel

Chiu, Yu-Hsiang; Spierings, Julia; van Laar, Jacob M; de Vries-Bouwstra, Jeska K; van Dijk, Marijke; Goldschmeding, Roel.

Afiliação

Chiu YH; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands; and Division of Rheumatology/Immunology/Allergy, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Spierings J; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.
van Laar JM; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.
de Vries-Bouwstra JK; The Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
van Dijk M; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands.
Goldschmeding R; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands. r.goldschmeding@umcutrecht.nl.

Clin Exp Rheumatol ; 41(8): 1612-1617, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37382464

Assuntos

Escleroderma Sistêmico; Humanos; Estudos Transversais; Escleroderma Sistêmico/patologia; Fibrose; Pele/patologia; Fibroblastos/metabolismo; Biópsia; Senescência Celular

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin Exp Rheumatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan

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