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Enteric tube position on preoperative radiographs predicts clinical outcomes in neonatal congenital diaphragmatic hernia with and without prenatal diagnosis.
Wallace, Marshall W; Niec, Jan A; Mirza, Muhammad B; Achey, Meredith A; Oros, Joseph; Danko, Melissa E; Hilmes, Melissa A; Hatch, L Dupree; Morris, Emily A; Lovvorn, Harold N.
Afiliação
  • Wallace MW; Vanderbilt University School of Medicine, Nashville, TN, USA. Mwwallace08@gmail.com.
  • Niec JA; Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Mirza MB; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Achey MA; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Oros J; Department of Radiology, Children's Hospital at Erlanger, Chattanooga, TN, USA.
  • Danko ME; Department of Pediatric Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
  • Hilmes MA; Division of Pediatric Radiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
  • Hatch LD; Division of Neonatology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
  • Morris EA; Division of Neonatology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
  • Lovvorn HN; Department of Pediatric Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
J Perinatol ; 43(9): 1131-1138, 2023 09.
Article em En | MEDLINE | ID: mdl-37391509
OBJECTIVE: Congenital Diaphragmatic Hernia (CDH) is diagnosed prenatally in ~60% of cases. Prenatal measures typically guide management and prognostication. Simple postnatal prognosticators are needed when prenatal diagnosis is lacking. We hypothesized that preoperative orogastric tube (OGT) tip position relative to the contralateral diaphragm correlates with defect severity, resource utilization, and clinical outcomes regardless of diagnostic status. STUDY DESIGN: 150 neonates with left-posterolateral CDH were analyzed. Impact of intrathoracic and intraabdominal preoperative tip position on clinical outcomes was compared. RESULTS: Ninety-nine neonates were prenatally diagnosed. Overall, intrathoracic position significantly correlated with larger diaphragmatic defects, advanced postnatal pulmonary support requirements (HFOV, pulmonary vasodilators, and ECMO), operative complexity, longer hospitalization, and poorer survival to discharge. These observations persisted when analyzing only cases lacking prenatal diagnosis. CONCLUSIONS: Preoperative OGT tip position predicts defect severity, resource utilization, and outcomes in CDH. This observation enhances postnatal prognostication and care planning for neonates without a prenatal diagnosis.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hérnias Diafragmáticas Congênitas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: J Perinatol Assunto da revista: PERINATOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hérnias Diafragmáticas Congênitas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: J Perinatol Assunto da revista: PERINATOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos