Lithium co-administration with rutin improves post-stroke neurological outcomes via suppressing Gsk-3ß activity in a rat model.

Rana, Anil Kumar; Kumar, Rajneesh; Shukla, Durgesh Nandan; Singh, Damanpreet

Rana, Anil Kumar; Kumar, Rajneesh; Shukla, Durgesh Nandan; Singh, Damanpreet.

Afiliação

Rana AK; Pharmacology and Toxicology Laboratory, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Kumar R; Pharmacology and Toxicology Laboratory, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Shukla DN; Pharmacology and Toxicology Laboratory, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, Himachal Pradesh, India.
Singh D; Pharmacology and Toxicology Laboratory, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: damanpreet@ihbt.res

Free Radic Biol Med ; 207: 107-119, 2023 10.

Article em En | MEDLINE | ID: mdl-37414348

Assuntos

Isquemia Encefálica; Fármacos Neuroprotetores; Traumatismo por Reperfusão; Acidente Vascular Cerebral; Ratos; Masculino; Animais; Glicogênio Sintase Quinase 3 beta/genética; Lítio/uso terapêutico; Rutina/farmacologia; Rutina/uso terapêutico; Óxido Nítrico/uso terapêutico; Acidente Vascular Cerebral/tratamento farmacológico; Isquemia Encefálica/genética; Traumatismo por Reperfusão/metabolismo; Fármacos Neuroprotetores/farmacologia; Fármacos Neuroprotetores/uso terapêutico

Palavras-chave

Blood-brain barrier damage; Cognitive deficits; Excitotoxicity; Gsk-3ß; NF-κB; Nrf2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Isquemia Encefálica / Fármacos Neuroprotetores / Acidente Vascular Cerebral Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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