68Ga-DOTA-peptide PET/CT for radiotherapy planning and evaluating treatment response in the management of meningiomas.
J Pak Med Assoc
; 73(6): 1340-1343, 2023 Jun.
Article
em En
| MEDLINE
| ID: mdl-37427649
ABSTRACT
Meningiomas overexpress somatostatin receptors (SSTR). PET imaging with SSTR ligands such as 68Ga-DOTA-peptide has recently shown high diagnostic accuracy in identification of meningiomas due to lack of normal bone and brain activity. PET-derived parameters, especially gross tumour volume (GTV) delineation improves inter-observer variability and appears to be particularly promising for RT planning. The potential strength of 68Ga-DOTA in the ongoing assessment of treatment response and disease progression in meningioma, particularly in the post-surgical and post-radiation settings is encouraging. More prospective randomized studies with large cohorts of patients are required to define the effective role of this modality.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
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Neoplasias Meníngeas
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Meningioma
Tipo de estudo:
Clinical_trials
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Observational_studies
Limite:
Humans
Idioma:
En
Revista:
J Pak Med Assoc
Ano de publicação:
2023
Tipo de documento:
Article