An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons &#945; and &#955;1 in HBV infection by promoting MAVS lysosomal degradation.

Zhang, Bin; Han, Haijun; Zhao, Xinyi; Li, Andria N; Wang, Yan; Yuan, Wenji; Yang, Zhongli; Li, Ming D

An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation.

Zhang, Bin; Han, Haijun; Zhao, Xinyi; Li, Andria N; Wang, Yan; Yuan, Wenji; Yang, Zhongli; Li, Ming D.

Afiliação

Zhang B; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Han H; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Zhao X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Li AN; Vanderbilt University School of Medicine, Nashville, TN, USA.
Wang Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Yuan W; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Yang Z; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi
Li MD; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Chi

EBioMedicine ; 94: 104694, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37442062

Assuntos

Carcinoma Hepatocelular; Hepatite B; Cininogênios; Neoplasias Hepáticas; Animais; Hepatite B/tratamento farmacológico; Hepatite B/genética; Vírus da Hepatite B; Interferon-alfa/farmacologia; Interferons; Replicação Viral; Humanos; Linhagem Celular; Cininogênios/genética

Palavras-chave

Functional SNP; HBV infection; Interferon; KNG1; Treatment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cininogênios / Carcinoma Hepatocelular / Hepatite B / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2023 Tipo de documento: Article

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