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IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory.
Micevic, Goran; Daniels, Andrew; Flem-Karlsen, Karine; Park, Koonam; Talty, Ronan; McGeary, Meaghan; Mirza, Haris; Blackburn, Holly N; Sefik, Esen; Cheung, Julie F; Hornick, Noah I; Aizenbud, Lilach; Joshi, Nikhil S; Kluger, Harriet; Iwasaki, Akiko; Bosenberg, Marcus W; Flavell, Richard A.
Afiliação
  • Micevic G; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Daniels A; Department of Dermatology, Yale School of Medicine, New Haven, CT 06520.
  • Flem-Karlsen K; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Park K; Department of Pathology, Yale School of Medicine, New Haven, CT 06520.
  • Talty R; Department of Dermatology, Yale School of Medicine, New Haven, CT 06520.
  • McGeary M; Department of Dermatology, Yale School of Medicine, New Haven, CT 06520.
  • Mirza H; Department of Pathology, Yale School of Medicine, New Haven, CT 06520.
  • Blackburn HN; Department of Pathology, Yale School of Medicine, New Haven, CT 06520.
  • Sefik E; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Cheung JF; Department of Pathology, Yale School of Medicine, New Haven, CT 06520.
  • Hornick NI; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Aizenbud L; Department of Surgery, Yale School of Medicine, New Haven, CT 06520.
  • Joshi NS; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Kluger H; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Iwasaki A; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520.
  • Bosenberg MW; Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520.
  • Flavell RA; Department of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT 06520.
Proc Natl Acad Sci U S A ; 120(30): e2304319120, 2023 07 25.
Article em En | MEDLINE | ID: mdl-37459511
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Melanoma Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Melanoma Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article