Minichromosome maintenance protein family member 6 mediates hepatocellular carcinoma progression by recruiting UBE3A to induce P53 ubiquitination.

Zhang, Xue; Bian, Saiyan; Ni, Yao; Zhou, Linlin; Yang, Chenyu; Zhang, Chenfeng; Sun, Xieyin; Xu, Nuo; Xu, Shiyu; Wang, Yilang; Gu, Shudong; Zheng, Wenjie

Zhang, Xue; Bian, Saiyan; Ni, Yao; Zhou, Linlin; Yang, Chenyu; Zhang, Chenfeng; Sun, Xieyin; Xu, Nuo; Xu, Shiyu; Wang, Yilang; Gu, Shudong; Zheng, Wenjie.

Afiliação

Zhang X; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China; Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Bian S; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Ni Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Zhou L; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Yang C; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China; Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Zhang C; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China; Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Sun X; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Xu N; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Xu S; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.
Wang Y; Department of Internal Medicine, The Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong, China. Electronic address: oncowang@ntu.edu.cn.
Gu S; Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China. Electronic address: gusdnt@ntu.edu.cn.
Zheng W; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China; Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China. Electronic address: wenjiezhen

Int J Biol Macromol ; 248: 125854, 2023 Sep 01.

Article em En | MEDLINE | ID: mdl-37460074

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/patologia; Neoplasias Hepáticas/patologia; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo; Proteínas de Manutenção de Minicromossomo/genética; Proteínas de Manutenção de Minicromossomo/metabolismo; Ubiquitinação; Família; Proliferação de Células; Linhagem Celular Tumoral; Regulação Neoplásica da Expressão Gênica; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

Hepatocellular carcinoma; MCM6; Molecular target

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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