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Immunostimulatory gene therapy targeting CD40, 4-1BB and IL-2R activates DCs and stimulates antigen-specific T-cell and NK-cell responses in melanoma models.
Wenthe, Jessica; Eriksson, Emma; Hellström, Ann-Charlotte; Moreno, Rafael; Ullenhag, Gustav; Alemany, Ramon; Lövgren, Tanja; Loskog, Angelica.
Afiliação
  • Wenthe J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsväg 20, 751 85, Uppsala, Sweden. jessica.wenthe@igp.uu.se.
  • Eriksson E; Lokon Pharma AB, Uppsala, Sweden. jessica.wenthe@igp.uu.se.
  • Hellström AC; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsväg 20, 751 85, Uppsala, Sweden.
  • Moreno R; Lokon Pharma AB, Uppsala, Sweden.
  • Ullenhag G; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsväg 20, 751 85, Uppsala, Sweden.
  • Alemany R; IDIBELL-Institute Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Lövgren T; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsväg 20, 751 85, Uppsala, Sweden.
  • Loskog A; Department of Oncology, Uppsala University Hospital, Uppsala, Sweden.
J Transl Med ; 21(1): 506, 2023 07 27.
Article em En | MEDLINE | ID: mdl-37501121
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suécia