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Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia.
Tsega, Wondale; Awoke, Worku; Sendekie, Ashenafi Kibret; Dagnew, Ephrem Mebratu; Bayih, Habtamu.
Afiliação
  • Tsega W; Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
  • Awoke W; Department of Epidemiology, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
  • Sendekie AK; Department of Clinical pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
  • Dagnew EM; Depatment of Pharmacy, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
  • Bayih H; Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
PLoS One ; 18(8): e0288698, 2023.
Article em En | MEDLINE | ID: mdl-37540698
ABSTRACT

BACKGROUND:

Myocardial infarction (MI) is diagnosed when there is a rise in cardiac biomarkers along with supportive evidence in the form of typical symptoms, suggestive electrocardiographic (ECG) changes, or imaging evidence of a new loss of viable myocardium or a new regional wall motion abnormality. The data regarding the use of ECG and echocardiography (Echo) findings and their impact on mortality are still lacking in Ethiopia. This study assessed the utilization of ECG and Echo findings and outcomes of patients with MI in tertiary care hospitals in Northwest Ethiopia.

METHODS:

A retrospective chart review was conducted on patients with MI who were admitted to the adult intensive care units (ICUs) of two selected hospitals between January 2018 and July 30, 2021. Data was entered and analyzed using the SPSS 25 software. Logistic regression analysis was used to assess the association between in-hospital mortality and other variables. A P-value < 0.05 was considered significant.

RESULTS:

Among the 203 participants, 67.5% were male, and the mean age of the participants was 59 (13.8). Around two-thirds (66.5%) of patients had STEMI and a regional all-motion abnormality. More than half (54.1%) of the cases were in the anteroapical region. For MI, there was a 23.2% inconsistency between ECG and Echo findings. The rate of in-hospital mortality for patients with MI was 23%. Pulmonary hypertension [AOR = 7.8, 95% CI 1.72-34.93], inferobasal regional wall motion abnormality [AOR = 7.9, 95% CI 1.340-46.093], Killip's classes III and IV [AOR = 2.7, 95% CI 1.103-6.314], infection [AOR = 3.2, 95% CI 1.108-10.65], and ischemic stroke [AOR = 1.9, 95% CI 1.091-5.222] were significantly associated with in-hospital mortality compared with their counterparts.

CONCLUSIONS:

The mortality of patients with MI in this study was higher than in other reports. Killip's class, pulmonary hypertension, infection, ischemic stroke, and inferobasal regional wall motion abnormalities were significantly associated with the in-hospital mortality of the patients with MI. There was a higher degree of inconsistency between ECG and Echo findings. The treatment of patients with MI should be tailored to their specific risk factors and causes.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão Pulmonar / Infarto do Miocárdio Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Africa Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Etiópia

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão Pulmonar / Infarto do Miocárdio Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Africa Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Etiópia