Injectable systems of chitosan in situ forming composite gel incorporating linezolid-loaded biodegradable nanoparticles for long-term treatment of bone infections.

Wassif, Reem Khaled; Elkheshen, Seham A; Shamma, Rehab Nabil; Amer, Mohammed S; Elhelw, Rehab; El-Kayal, Maha

Wassif, Reem Khaled; Elkheshen, Seham A; Shamma, Rehab Nabil; Amer, Mohammed S; Elhelw, Rehab; El-Kayal, Maha.

Afiliação

Wassif RK; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt.
Elkheshen SA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr Elini Street, Cairo, 11562, Egypt. seham.elkheshen@pharma.cu.edu.eg.
Shamma RN; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr Elini Street, Cairo, 11562, Egypt.
Amer MS; Department of Surgery, Anaesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt.
Elhelw R; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt.
El-Kayal M; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt.

Drug Deliv Transl Res ; 14(1): 80-102, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37542190

Assuntos

Quitosana; Nanopartículas; Humanos; Linezolida; Hidrogéis; Poliésteres

Palavras-chave

Biodegradable nanoparticles; Bone infections; Chitosan in situ forming gel; Linezolid; Osteomyelitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quitosana / Nanopartículas Limite: Humans Idioma: En Revista: Drug Deliv Transl Res Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Egito

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