Diffusion tensor imaging of the physis: the ABC's.
Pediatr Radiol
; 53(12): 2355-2368, 2023 11.
Article
em En
| MEDLINE
| ID: mdl-37658251
ABSTRACT
The physis, or growth plate, is the primary structure responsible for longitudinal growth of the long bones. Diffusion tensor imaging (DTI) is a technique that depicts the anisotropic motion of water molecules, or diffusion. When diffusion is limited by cellular membranes, information on tissue microstructure can be acquired. Tractography, the visual display of the direction and magnitude of water diffusion, provides qualitative visualization of complex cellular architecture as well as quantitative diffusion metrics that appear to indirectly reflect physeal activity. In the growing bones, DTI depicts the columns of cartilage and new bone in the physeal-metaphyseal complex. In this "How I do It", we will highlight the value of DTI as a clinical tool by presenting DTI tractography of the physeal-metaphyseal complex of children and adolescents during normal growth, illustrating variation in qualitative and quantitative tractography metrics with age and skeletal location. In addition, we will present tractography from patients with physeal dysfunction caused by growth hormone deficiency and physeal injury due to trauma, chemotherapy, and radiation therapy. Furthermore, we will delineate our process, or "DTI pipeline," from image acquisition to data interpretation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imagem de Tensor de Difusão
/
Lâmina de Crescimento
Tipo de estudo:
Qualitative_research
Limite:
Adolescent
/
Child
/
Humans
Idioma:
En
Revista:
Pediatr Radiol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos