Your browser doesn't support javascript.
loading
Biphasic pleural mesothelioma in a goat.
Fry, Lindsay M; DenHerder, Johnathan; Clyde, Gay Lynn; Williams, Laura A; Schneider, David A.
Afiliação
  • Fry LM; Animal Disease Research Unit, U.S. Department of Agriculture - Agricultural Research Service, Pullman, Washington 99164, USA (Fry, Schneider); Veterinary Microbiology and Pathology Department (Fry, Williams, Schneider) and Office of the Campus Veterinarian (DenHerder, Clyde), Washington State Univer
  • DenHerder J; Animal Disease Research Unit, U.S. Department of Agriculture - Agricultural Research Service, Pullman, Washington 99164, USA (Fry, Schneider); Veterinary Microbiology and Pathology Department (Fry, Williams, Schneider) and Office of the Campus Veterinarian (DenHerder, Clyde), Washington State Univer
  • Clyde GL; Animal Disease Research Unit, U.S. Department of Agriculture - Agricultural Research Service, Pullman, Washington 99164, USA (Fry, Schneider); Veterinary Microbiology and Pathology Department (Fry, Williams, Schneider) and Office of the Campus Veterinarian (DenHerder, Clyde), Washington State Univer
  • Williams LA; Animal Disease Research Unit, U.S. Department of Agriculture - Agricultural Research Service, Pullman, Washington 99164, USA (Fry, Schneider); Veterinary Microbiology and Pathology Department (Fry, Williams, Schneider) and Office of the Campus Veterinarian (DenHerder, Clyde), Washington State Univer
  • Schneider DA; Animal Disease Research Unit, U.S. Department of Agriculture - Agricultural Research Service, Pullman, Washington 99164, USA (Fry, Schneider); Veterinary Microbiology and Pathology Department (Fry, Williams, Schneider) and Office of the Campus Veterinarian (DenHerder, Clyde), Washington State Univer
Can Vet J ; 64(9): 828-832, 2023 09.
Article em En | MEDLINE | ID: mdl-37663018
ABSTRACT
An 8-year-old Saanen goat doe was seen for inappetence, tachycardia, and intermittent bluish-grey discoloration of the oral mucous membranes. On physical examination, the goat was mildly tachypneic and tachycardic, with reduced sounds auscultated on the left side of the thorax. Euthanasia was elected. Necropsy revealed an infiltrative, multinodular mass within the left thoracic cavity and innumerable small, tan nodules disseminated across the pleura of the lungs, thoracic walls, and diaphragm. Upon histologic examination, the mass was composed of highly pleomorphic, fusiform to polygonal cells. Neoplastic cells exhibited positive immunoreactivity for both cytokeratin and vimentin, consistent with a diagnosis of biphasic pleural mesothelioma. Key clinical message Mesothelioma has rarely been described in the goat but should be considered as a differential diagnosis for thoracic masses in small ruminants, along with thymoma; metastatic neoplasia; carcinomatosis; and granulomatous lesions caused by parasites, bacteria, and fungi.
Mésothéliome pleural biphasique chez une chèvre. Une chèvre Saanen âgée de 8 ans a été vue pour de l'inappétence, une tachycardie et une décoloration gris bleuâtre intermittente des muqueuses buccales. À l'examen physique, la chèvre était légèrement tachypnéique et tachycardique, avec des sons réduits auscultés du côté gauche du thorax. Il a été décidé d'euthanasier l'animal. L'autopsie a révélé une masse multinodulaire infiltrante dans la cavité thoracique gauche et d'innombrables petits nodules brun clair disséminés à travers la plèvre pulmonaire, les parois thoraciques et le diaphragme. À l'examen histologique, la masse était composée de cellules hautement pléomorphes, fusiformes à polygonales. Les cellules néoplasiques ont présenté une immunoréactivité positive pour la cytokératine et la vimentine, compatible avec un diagnostic de mésothéliome pleural biphasique.Message clinique cléLe mésothéliome a rarement été décrit chez la chèvre mais doit être considéré comme un diagnostic différentiel des masses thoraciques chez les petits ruminants, avec le thymome, la néoplasie métastatique, la carcinomatose et les lésions granulomateuses causées par des parasites, des bactéries et des champignons.(Traduit par Dr Serge Messier).
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma / Doenças das Cabras / Mesotelioma Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Can Vet J Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma / Doenças das Cabras / Mesotelioma Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Can Vet J Ano de publicação: 2023 Tipo de documento: Article