Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold.

Gaudreault, Francis; Baardsnes, Jason; Martynova, Yuliya; Dachon, Aurore; Hogues, Hervé; Corbeil, Christopher R; Purisima, Enrico O; Arbour, Mélanie; Sulea, Traian

Gaudreault, Francis; Baardsnes, Jason; Martynova, Yuliya; Dachon, Aurore; Hogues, Hervé; Corbeil, Christopher R; Purisima, Enrico O; Arbour, Mélanie; Sulea, Traian.

Afiliação

Gaudreault F; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Baardsnes J; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Martynova Y; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Dachon A; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Hogues H; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Corbeil CR; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Purisima EO; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Arbour M; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
Sulea T; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.

Front Mol Biosci ; 10: 1253689, 2023.

Article em En | MEDLINE | ID: mdl-37692063

Palavras-chave

DARPin; ProPOSE; binding affinity; protein-protein docking; rigid backbone

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Front Mol Biosci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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