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Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry.
Agosti, Pasquale; De Leo, Pasqualina; Capecchi, Marco; Ferrari, Barbara; Mancini, Ilaria; Gattillo, Salvatore; Trisolini, Silvia Maria; Rinaldi, Erminia; Podda, Gian Marco; Prezioso, Lucia; Salutari, Prassede; Facchini, Luca; Caramazza, Domenica; Tolomelli, Giulia; Artoni, Andrea; Peyvandi, Flora.
Afiliação
  • Agosti P; Department of Pathophysiology and Transplantation, and Fondazione Luigi Villa, Università degli Studi di Milano, Milan, Italy.
  • De Leo P; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Capecchi M; Clinica Moncucco, Hematology Service, Lugano, Switzerland.
  • Ferrari B; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Mancini I; Department of Pathophysiology and Transplantation, and Fondazione Luigi Villa, Università degli Studi di Milano, Milan, Italy.
  • Gattillo S; Immuno-Hematology and Transfusion Medicine Unit, San Raffaele Hospital, Milan, Italy.
  • Trisolini SM; Hematology, Department of Translational and Precision Medicine, "Sapienza" University of Rome, Rome, Italy.
  • Rinaldi E; Hematology Unit, A. Perrino Hospital, Brindisi, Italy.
  • Podda GM; U.O.C. Medicina II, ASST Santi Paolo e Carlo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.
  • Prezioso L; Haematology and BMT Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
  • Salutari P; Ospedale Civile "Spirito Santo", Pescara, Italy.
  • Facchini L; Hematology Unit, Azienda USL-IRCCS di Reggio Emilia, Viale Umberto I n, 50 42123 Reggio Emilia, Italy.
  • Caramazza D; Hematology, University Hospital "Ospedale di Circolo e Fondazione Macchi" - ASST Sette Laghi, Viale L. Borri 57, 21100, Varese, Italy.
  • Tolomelli G; Unit of Hematology, Rimini Hospital "Infermi", Rimini, Italy.
  • Artoni A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Peyvandi F; Department of Pathophysiology and Transplantation, and Fondazione Luigi Villa, Università degli Studi di Milano, Milan, Italy.
Res Pract Thromb Haemost ; 7(6): 102185, 2023 Aug.
Article em En | MEDLINE | ID: mdl-37720483
ABSTRACT
•Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode.•Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting.•Two major bleeds leading to drug discontinuation were observed.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Res Pract Thromb Haemost Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Res Pract Thromb Haemost Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália