PERK-mediated antioxidant response is key for pathogen persistence in ticks.

Rosche, Kristin L; Hurtado, Joanna; Fisk, Elis A; Vosbigian, Kaylee A; Warren, Ashley L; Sidak-Loftis, Lindsay C; Wright, Sarah J; Ramirez-Zepp, Elisabeth; Park, Jason M; Shaw, Dana K

Rosche, Kristin L; Hurtado, Joanna; Fisk, Elis A; Vosbigian, Kaylee A; Warren, Ashley L; Sidak-Loftis, Lindsay C; Wright, Sarah J; Ramirez-Zepp, Elisabeth; Park, Jason M; Shaw, Dana K.

Afiliação

Rosche KL; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Hurtado J; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Fisk EA; School of Molecular Biosciences, Washington State University , Pullman, Washington, USA.
Vosbigian KA; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Warren AL; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Sidak-Loftis LC; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Wright SJ; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Ramirez-Zepp E; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Park JM; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Shaw DK; Department of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.

mSphere ; 8(5): e0032123, 2023 10 24.

Article em En | MEDLINE | ID: mdl-37733353

Assuntos

Anaplasma phagocytophilum; Anaplasmose; Borrelia burgdorferi; Ixodes; Doença de Lyme; Animais; Antioxidantes/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; Ixodes/microbiologia; Borrelia burgdorferi/genética; Anaplasma phagocytophilum/genética; Nitrogênio/metabolismo; Oxigênio/metabolismo

Palavras-chave

ATF4; Anaplasma phagocytophilum; Borrelia burgdorferi; Ixodes scapularis; Nrf2; PERK; antioxidant response; eIF2α; tick-borne disease; vector competence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Lyme / Ixodes / Borrelia burgdorferi / Anaplasma phagocytophilum / Anaplasmose Limite: Animals Idioma: En Revista: MSphere Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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