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Prognostic Assessment of Gastropancreatic Neuroendocrine Neoplasm: Prospects and Limits of Radiomics.
De Muzio, Federica; Pellegrino, Fabio; Fusco, Roberta; Tafuto, Salvatore; Scaglione, Mariano; Ottaiano, Alessandro; Petrillo, Antonella; Izzo, Francesco; Granata, Vincenza.
Afiliação
  • De Muzio F; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
  • Pellegrino F; Radiology Division, S. Bonifacio Hospital, 37047 Verona, Italy.
  • Fusco R; Medical Oncology Division, Igea SpA, 80013 Napoli, Italy.
  • Tafuto S; Unit of Sarcomi e Tumori Rari, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.
  • Scaglione M; Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.
  • Ottaiano A; Unit for Innovative Therapies of Abdominal Metastastes, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.
  • Petrillo A; Division of Radiology, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.
  • Izzo F; Division of Hepatobiliary Surgery, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.
  • Granata V; Division of Radiology, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.
Diagnostics (Basel) ; 13(18)2023 Sep 07.
Article em En | MEDLINE | ID: mdl-37761243
Neuroendocrine neoplasms (NENs) are a group of lesions originating from cells of the diffuse neuroendocrine system. NENs may involve different sites, including the gastrointestinal tract (GEP-NENs). The incidence and prevalence of GEP-NENs has been constantly rising thanks to the increased diagnostic power of imaging and immuno-histochemistry. Despite the plethora of biochemical markers and imaging techniques, the prognosis and therapeutic choice in GEP-NENs still represents a challenge, mainly due to the great heterogeneity in terms of tumor lesions and clinical behavior. The concept that biomedical images contain information about tissue heterogeneity and pathological processes invisible to the human eye is now well established. From this substrate comes the idea of radiomics. Computational analysis has achieved promising results in several oncological settings, and the use of radiomics in different types of GEP-NENs is growing in the field of research, yet with conflicting results. The aim of this narrative review is to provide a comprehensive update on the role of radiomics on GEP-NEN management, focusing on the main clinical aspects analyzed by most existing reports: predicting tumor grade, distinguishing NET from other tumors, and prognosis assessment.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Diagnostics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Diagnostics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália