Dual-targeted delivery system using hollow silica nanoparticles with H<sup>+</sup>-triggered bubble generating characteristic coated with hyaluronic acid and AS1411 for cancer therapy.

Mirzaei, Salimeh; Khademi, Zahra; Zolfaghari, Reza; Ramezani, Mohammad; Alibolandi, Mona; Abnous, Khalil; Taghdisi, Seyed Mohammad

Dual-targeted delivery system using hollow silica nanoparticles with H⁺-triggered bubble generating characteristic coated with hyaluronic acid and AS1411 for cancer therapy.

Mirzaei, Salimeh; Khademi, Zahra; Zolfaghari, Reza; Ramezani, Mohammad; Alibolandi, Mona; Abnous, Khalil; Taghdisi, Seyed Mohammad.

Afiliação

Mirzaei S; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Khademi Z; Department of Medicinal Chemistry, Faculty of Pharmacy, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Zolfaghari R; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Ramezani M; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Alibolandi M; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Abnous K; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Taghdisi SM; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Drug Dev Ind Pharm ; 49(10): 648-657, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37772892

Assuntos

Neoplasias da Mama; Nanopartículas; Cricetinae; Humanos; Animais; Camundongos; Feminino; Ácido Hialurônico; Células CHO; Sistemas de Liberação de Medicamentos/métodos; Linhagem Celular Tumoral; Cricetulus; Dióxido de Silício/química; Epirubicina; Nanopartículas/química; Células MCF-7; Neoplasias da Mama/tratamento farmacológico

Palavras-chave

AS1411 aptamer; Targeting aptamer; chemotherapy drug; nanocomplex; silica nanoparticles with hollow structures

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Nanopartículas Limite: Animals / Female / Humans Idioma: En Revista: Drug Dev Ind Pharm Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã

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