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Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells.
Conole, Daniel; Cao, Fangyuan; Am Ende, Christopher W; Xue, Liang; Kantesaria, Sheila; Kang, Dahye; Jin, Jun; Owen, Dafydd; Lohr, Linda; Schenone, Monica; Majmudar, Jaimeen D; Tate, Edward W.
Afiliação
  • Conole D; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London, W12 0BZ, United Kingdom.
  • Cao F; Present address: Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, 1023, New Zealand.
  • Am Ende CW; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London, W12 0BZ, United Kingdom.
  • Xue L; Pfizer Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, Connecticut, 06340, USA.
  • Kantesaria S; Pfizer Worldwide Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts, 2139, USA.
  • Kang D; Pfizer Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, Connecticut, 06340, USA.
  • Jin J; Pfizer Worldwide Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts, 2139, USA.
  • Owen D; BioDuro, No.233 North FuTe Rd., WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R. China.
  • Lohr L; Pfizer Worldwide Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts, 2139, USA.
  • Schenone M; Pfizer Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, Connecticut, 06340, USA.
  • Majmudar JD; Pfizer Worldwide Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts, 2139, USA.
  • Tate EW; Pfizer Worldwide Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts, 2139, USA.
Angew Chem Int Ed Engl ; 62(47): e202311190, 2023 11 20.
Article em En | MEDLINE | ID: mdl-37779326
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / Complexo de Endopeptidases do Proteassoma Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / Complexo de Endopeptidases do Proteassoma Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido