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Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus.
Kou, Buyu; Zhang, Zhisen; Han, Xingchun; Zhou, Zheng; Xu, Zhiheng; Zhou, Xue; Shen, Fang; Zhou, Yuan; Tian, Xiaojun; Yang, Guang; Young, John A T; Qiu, Hongxia; Ottaviani, Giorgio; Mayweg, Alexander; Zhu, Wei; Shen, Hong C; Liu, Haixia; Hu, Taishan.
Afiliação
  • Kou B; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Zhang Z; Medicinal Chemistry, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Han X; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Zhou Z; Medicinal Chemistry, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Xu Z; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Zhou X; Medicinal Chemistry, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Shen F; Medicinal Chemistry, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Zhou Y; Lead Discovery, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Tian X; Medicinal Chemistry, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Yang G; Lead Discovery, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Young JAT; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Qiu H; Discovery Virology, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Ottaviani G; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Mayweg A; Discovery Virology, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Zhu W; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Shen HC; Discovery Virology, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Liu H; China Innovation Center of Roche, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
  • Hu T; Discovery Virology, Building 5, 371 Lishizhen Road, Shanghai 201203, China.
J Med Chem ; 66(20): 14116-14132, 2023 10 26.
Article em En | MEDLINE | ID: mdl-37801325
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite B Crônica / Hepatite B Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite B Crônica / Hepatite B Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China