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Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial.
Harrison, Stephen A; Frias, Juan P; Neff, Guy; Abrams, Gary A; Lucas, K Jean; Sanchez, William; Gogia, Sudhanshu; Sheikh, Muhammed Y; Behling, Cynthia; Bedossa, Pierre; Shao, Lan; Chan, Doreen; Fong, Erica; de Temple, Brittany; Shringarpure, Reshma; Tillman, Erik J; Rolph, Timothy; Cheng, Andrew; Yale, Kitty.
Afiliação
  • Harrison SA; Department of Hepatology, University of Oxford, Oxford, UK; Pinnacle Clinical Research, San Antonio, TX, USA.
  • Frias JP; Velocity Clinical Research, Los Angeles, CA, USA.
  • Neff G; Covenant Metabolic Specialists, Sarasota, FL, USA.
  • Abrams GA; Department of Medicine, Prisma Health Upstate, Greenville, SC, USA.
  • Lucas KJ; Lucas Research, Morehead, NC, USA.
  • Sanchez W; Floridian Clinical Research, Miami Lakes, FL, USA.
  • Gogia S; Texas Digestive Disease Institute, Webster, TX, USA.
  • Sheikh MY; Fresno Clinical Research Center, Fresno, CA, USA.
  • Behling C; Department of Pathology, Sharp Memorial Hospital, San Diego, CA, USA.
  • Bedossa P; Liverpat, Paris, France; Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, UK.
  • Shao L; Statistics, Labcorp, Burlington, NC, USA.
  • Chan D; Akero Therapeutics, South San Francisco, CA, USA.
  • Fong E; Akero Therapeutics, South San Francisco, CA, USA.
  • de Temple B; Akero Therapeutics, South San Francisco, CA, USA.
  • Shringarpure R; Akero Therapeutics, South San Francisco, CA, USA. Electronic address: reshma@akerotx.com.
  • Tillman EJ; Akero Therapeutics, South San Francisco, CA, USA.
  • Rolph T; Akero Therapeutics, South San Francisco, CA, USA.
  • Cheng A; Akero Therapeutics, South San Francisco, CA, USA.
  • Yale K; Akero Therapeutics, South San Francisco, CA, USA.
Lancet Gastroenterol Hepatol ; 8(12): 1080-1093, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37802088
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Gastroenterol Hepatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Gastroenterol Hepatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos