The gut microbiota and coronary artery calcification in Japanese men.
Am Heart J
; 267: 12-21, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-37805105
ABSTRACT
BACKGROUND:
The gut microbiota differs between patients with coronary artery disease (CAD) and healthy controls; however, it currently remains unclear whether these differences exist prior to the onset of CAD. We herein investigated the gut microbiota associated with subclinical coronary artery calcification (CAC) in a Japanese population.METHODS:
A total of 663 Japanese men were enrolled in this cross-sectional study. Computed tomography and gut microbiology tests were performed, and CAC scores were calculated using the Agatston method. Participants were categorized into 4 groups based on their CAC scores CAC = 0, 0RESULTS:
The mean age of participants was 68.4 years (46-83 years). The numbers of participants in CAC = 0, 0CONCLUSIONS:
The gut microbiota significantly differed from the phylum to genus level in a manner that was dependent on CAC scores, even before the onset of CAD.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Calcificação Vascular
/
Microbioma Gastrointestinal
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Am Heart J
Ano de publicação:
2024
Tipo de documento:
Article