Novel insight into the etiology of ischemic stroke gained by integrative multiome-wide association study.

Jung, Junghyun; Lu, Zeyun; de Smith, Adam; Mancuso, Nicholas

Jung, Junghyun; Lu, Zeyun; de Smith, Adam; Mancuso, Nicholas.

Afiliação

Jung J; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, United States.
Lu Z; Biostatistics Division, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 2001 North Soto Street, Los Angeles, CA 90033, United States.
de Smith A; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, United States.
Mancuso N; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, United States.

Hum Mol Genet ; 33(2): 170-181, 2024 Jan 07.

Article em En | MEDLINE | ID: mdl-37824084

Assuntos

AVC Isquêmico; Transcriptoma; Humanos; Estudo de Associação Genômica Ampla; AVC Isquêmico/genética; Genômica; Fenótipo; Predisposição Genética para Doença; Polimorfismo de Nucleotídeo Único/genética

Palavras-chave

drug repositioning; ischemic stroke; multiome-wide association study; phenome-wide association study and genetic correlation analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcriptoma / AVC Isquêmico Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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