Multi-omics analysis of metastatic pancreatic cancer reveals an immunosuppressive landscape.

Steele, Nina G; Hartway, Kailee M

Steele, Nina G; Hartway, Kailee M.

Afiliação

Steele NG; Henry Ford Pancreatic Cancer Center, Department of Surgery, Henry Ford Hospital, Detroit, MI 48202, USA; Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48202, USA; Deparment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA. Electronic address: nsteele1@hfhs.org.
Hartway KM; Henry Ford Pancreatic Cancer Center, Department of Surgery, Henry Ford Hospital, Detroit, MI 48202, USA; Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48202, USA. Electronic address: khartwa1@hfhs.org.

Med ; 4(10): 657-659, 2023 10 13.

Article em En | MEDLINE | ID: mdl-37837960

ABSTRACT

ABSTRACT

Immune cell populations play key functional roles in tumor growth and metastasis, and multi-omic approaches can map cellular interactions to identify targets for highly immunosuppressive and treatment resistant cancers. In this issue of Med, Zhang et al.1 investigate the immune cell landscape of advanced pancreatic cancer to understand the mechanisms underlying liver metastasis.

Assuntos

Neoplasias Hepáticas; Neoplasias Pancreáticas; Humanos; Multiômica; Neoplasias Pancreáticas/genética; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/secundário; Comunicação Celular

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Med Ano de publicação: 2023 Tipo de documento: Article

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