Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts.
Mol Cell Biol
; 6(8): 2990-3, 1986 Aug.
Article
em En
| MEDLINE
| ID: mdl-3785220
ABSTRACT
Nuclear microinjection of c-H-ras DNA induced DNA synthesis in reversibly nonproliferating quiescent human cells. The proto-oncogene and oncogene forms were equally effective inducers. In contrast, c-H-ras DNA either alone or in combination with the adenovirus E1A gene did not cause terminally nondividing senescent cells to synthesize DNA.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oncogenes
/
Proto-Oncogenes
/
DNA
/
Fibroblastos
Limite:
Humans
Idioma:
En
Revista:
Mol Cell Biol
Ano de publicação:
1986
Tipo de documento:
Article