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Heterologous expression of fungal L-asparaginase: a systematic review.
Rodrigues Andrade, Kellen Cruvinel; Cordeiro de Abreu, Joel Antonio; Guimarães, Marina Borges; Abrunhosa, Letícia Santos; Leôncio Rodrigues, Ana Luisa; Fonseca-Bazzo, Yris Maria; Silveira, Damaris; Souza, Paula Monteiro; Magalhães, Pérola Oliveira.
Afiliação
  • Rodrigues Andrade KC; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Cordeiro de Abreu JA; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Guimarães MB; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Abrunhosa LS; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Leôncio Rodrigues AL; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Fonseca-Bazzo YM; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Silveira D; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Souza PM; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
  • Magalhães PO; Laboratory of Natural Products, Health Science School, University of Brasília, Brasília, 70910-900, Brazil.
Future Microbiol ; 19: 157-171, 2024 Jan.
Article em En | MEDLINE | ID: mdl-37882841
Asparaginase is a common treatment for the most common type of leukemia in children. These treatments generally use asparaginase sourced from bacteria. Some people can experience bad reactions to these treatments. One way that has been explored to avoid this is to use asparaginase sourced from fungi because they are more similar to humans. However, fungi produce less asparaginase than bacteria. This review looks into ways that the production of fungal asparaginases can be made more productive.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: Future Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: Future Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil