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Novel technique for arterial reconstruction in simultaneous pancreas-kidney transplantation, a randomized clinical trial.
Karar, Hassan; Shafiekhani, Mojtaba; Mahmoudi, Mohamad Mahdi; Azadeh, Nazanin; Shamsaeefar, Alireza; Nazari, Sahar Sohrabi; Jafari, Mehran; Ashrafzadeh, Kiarash; Esmaeili, Maryam; Nikeghbalian, Saman; Nikoupour, Hamed.
Afiliação
  • Karar H; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shafiekhani M; Department of Hepatobiliary and Transplant Surgery, The National Center of Gastrointestinal and Liver Disease, Ibn-Sina Specialized Hospital, Khartoum, Sudan.
  • Mahmoudi MM; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Azadeh N; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shamsaeefar A; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Nazari SS; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Jafari M; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Ashrafzadeh K; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Esmaeili M; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Nikeghbalian S; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Nikoupour H; Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC Res Notes ; 16(1): 295, 2023 Oct 26.
Article em En | MEDLINE | ID: mdl-37885028
INTRODUCTION: Simultaneous pancreas kidney (SPK) transplantation is an invaluable procedure to enhance the quality of life of insulin-dependent patients with advanced renal disease. The creation of vascular anastomoses of the donor's pancreas vessels to the recipient's, is of utmost importance to predict the graft outcome and surgical complications. In the study we introduce a novel technique for arterial reconstruction during SPK transplantation. METHODS: Conventionally, during the SPK transplantation, a so-called Y-graft is anastomosed between donor's superior mesenteric and splenic artery to the recipient's right iliac artery. In the study we adopted a new technique by preparing an extra extension using the donor's carotid artery, to be anastomosed to the Y-graft and the iliac artery. In this non-blinded randomized clinical trial we compared the surgical complications and early outcomes between the 2 groups of patients with the traditional and new arterial reconstruction techniques during 3 months after transplantation. RESULTS: Thirty adult patients were included in the study. The incidence of pancreatitis, vascular thrombosis and surgical site infection was lower in the new Y-graft and extension technique, which was not statistically significant. However, the calculated Cohen's d index showed the medium effect of new Y-graft and extension technique on complication after SPK transplantations. CONCLUSION: The post-operative complications tend to be lower in the novel arterial reconstruction technique, however a study on a larger patient group is encouraged to confirm our primary results. TRIAL REGISTRATION: The study was registered at the Iranian Registry of Clinical Trials on 12/05/2022; IRCT 20210625051701N2; ( http://www.irct.ir/ ).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Transplante de Rim / Diabetes Mellitus Tipo 1 Limite: Adult / Humans País/Região como assunto: Asia Idioma: En Revista: BMC Res Notes Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Transplante de Rim / Diabetes Mellitus Tipo 1 Limite: Adult / Humans País/Região como assunto: Asia Idioma: En Revista: BMC Res Notes Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã