Adiposomes from Obese-Diabetic Individuals Promote Endothelial Dysfunction and Loss of Surface Caveolae.

Mirza, Imaduddin; Haloul, Mohamed; Hassan, Chandra; Masrur, Mario; Mostafa, Amro; Bianco, Francesco M; Ali, Mohamed M; Minshall, Richard D; Mahmoud, Abeer M

Mirza, Imaduddin; Haloul, Mohamed; Hassan, Chandra; Masrur, Mario; Mostafa, Amro; Bianco, Francesco M; Ali, Mohamed M; Minshall, Richard D; Mahmoud, Abeer M.

Afiliação

Mirza I; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Haloul M; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Hassan C; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Masrur M; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Mostafa A; Departments of Anesthesiology and Pharmacology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Bianco FM; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Ali MM; School of Business and Non-Profit Management, North Park University, Chicago, IL 60625, USA.
Minshall RD; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Mahmoud AM; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

Cells ; 12(20)2023 10 15.

Article em En | MEDLINE | ID: mdl-37887297

Assuntos

Diabetes Mellitus Tipo 2; Doenças Vasculares; Humanos; Cavéolas/metabolismo; Células Endoteliais/metabolismo; Gotículas Lipídicas/metabolismo; Transdução de Sinais; Quinases da Família src/metabolismo; Doenças Vasculares/metabolismo; Diabetes Mellitus Tipo 2/metabolismo

Palavras-chave

Src kinase; adiposomes; caveolae; caveolin-1 (cav-1); endothelial dysfunction; endothelial nitric oxide synthase (eNOS); extracellular vesicles; flow-induced dilation (FID); glycosphingolipids (GSLs); shear stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Diabetes Mellitus Tipo 2 Limite: Humans Idioma: En Revista: Cells Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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