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Serum Cytokine Changes in a Patient with Chronic Pulmonary Aspergillosis Overlapping with Allergic Bronchopulmonary Aspergillosis: A Case Report.
Tsukamoto, Yusei; Ito, Yuya; Obase, Yasushi; Takazono, Takahiro; Nakada, Nana; Ashizawa, Nobuyuki; Hirayama, Tatsuro; Takeda, Kazuaki; Ide, Shotaro; Iwanaga, Naoki; Tashiro, Masato; Hosogaya, Naoki; Fukahori, Susumu; Fukushima, Chizu; Yanagihara, Katsunori; Izumikawa, Koichi; Mukae, Hiroshi.
Afiliação
  • Tsukamoto Y; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Ito Y; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Obase Y; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Takazono T; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
  • Nakada N; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Ashizawa N; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.
  • Hirayama T; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Takeda K; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Ide S; Infection Control and Education Center, Nagasaki University Hospital, Japan.
  • Iwanaga N; Department of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Japan.
  • Tashiro M; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Hosogaya N; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Fukahori S; Infectious Diseases Experts Training Center, Nagasaki University Hospital, Japan.
  • Fukushima C; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Yanagihara K; Department of Respiratory Medicine, Nagasaki University Hospital, Japan.
  • Izumikawa K; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.
  • Mukae H; Infection Control and Education Center, Nagasaki University Hospital, Japan.
Intern Med ; 2023 Oct 27.
Article em En | MEDLINE | ID: mdl-37899245
ABSTRACT
Allergic bronchopulmonary aspergillosis (ABPA) and chronic pulmonary aspergillosis (CPA) are diseases caused by Aspergillus infection, and CPA can develop from ABPA in some cases. We herein report a patient with CPA overlapping with ABPA. Serum cytokine levels were evaluated at 4 time points the ABPA diagnosis, CPA diagnosis, 6 months after the start of voriconazole (VRCZ), and 12 months after re-administration of VRCZ. Interleukin (IL)-13 levels decreased upon glucocorticoid treatment, whereas IL-25 and IL-33 levels decreased rapidly with the initiation of antifungals. Early antifungal therapy may be important to control disease progression and prevent CPA overlap.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão