Inhibition of Galectin-3 in a Rat Model of Epilepsy and Kainate-Activated BV2 Cells Limits Microglial Activation Through the NLRP3/Pyroptosis Pathway.

Sun, Weiwei; Hao, Ying; Li, Chunxiang; Zhao, Yuanyuan; Yu, Haishao; Wang, Lin

Sun, Weiwei; Hao, Ying; Li, Chunxiang; Zhao, Yuanyuan; Yu, Haishao; Wang, Lin.

Afiliação

Sun W; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.
Hao Y; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.
Li C; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.
Zhao Y; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.
Yu H; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.
Wang L; Department of Pediatrics, Yantai Yuhuangding Hospital, Yantai, China.

Neuroimmunomodulation ; 30(1): 325-337, 2023.

Article em En | MEDLINE | ID: mdl-37926077

Assuntos

Epilepsia; Galectina 3; Animais; Ratos; Citocinas; Epilepsia/induzido quimicamente; Ácido Caínico/toxicidade; Microglia; Proteína 3 que Contém Domínio de Pirina da Família NLR; Piroptose; Ratos Sprague-Dawley; RNA Interferente Pequeno; Convulsões

Palavras-chave

Epilepsy; Galectin-3; NLRP3; Neuroinflammation; Pyroptosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Galectina 3 / Epilepsia Limite: Animals Idioma: En Revista: Neuroimmunomodulation Assunto da revista: ALERGIA E IMUNOLOGIA / NEUROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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