[Progress of genomic mutation spectrum in biliary tract malignant tumors].
Zhonghua Wai Ke Za Zhi
; 61(12): 1124-1129, 2023 Dec 01.
Article
em Zh
| MEDLINE
| ID: mdl-37932150
ABSTRACT
Biliary tract cancer is characterized by high invasiveness, occult early clinical manifestations and rapid progression. Surgical resection typically fails to achieve satisfactory outcomes. Biliary tract cancer exhibits low sensitivity to radiotherapy and chemotherapy. The prognosis of patients is extremely poor. Genomics research based on next-generation sequencing technology has made some advances. The gene mutation spectrum of biliary tract cancer has been preliminarily revealed, which lays a foundation for the study of molecular typing. This review summarizes the research progress and clinical application of gene mutation spectrum of biliary tract cancer in recent years, aiming to provide reference for the clinical diagnosis, treatment and basic research.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistema Biliar
/
Neoplasias do Sistema Biliar
Limite:
Humans
Idioma:
Zh
Revista:
Zhonghua Wai Ke Za Zhi
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China