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The shared genetic architecture and evolution of human language and musical rhythm.
Alagöz, Gökberk; Eising, Else; Mekki, Yasmina; Bignardi, Giacomo; Fontanillas, Pierre; Nivard, Michel G; Luciano, Michelle; Cox, Nancy J; Fisher, Simon E; Gordon, Reyna L.
Afiliação
  • Alagöz G; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.
  • Eising E; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.
  • Mekki Y; Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Bignardi G; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Fontanillas P; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, The Netherlands.
  • Nivard MG; 23andMe, Inc., Sunnyvale, CA, USA.
  • Cox NJ; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
  • Fisher SE; Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Gordon RL; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
bioRxiv ; 2023 Nov 02.
Article em En | MEDLINE | ID: mdl-37961248
ABSTRACT
Rhythm and language-related traits are phenotypically correlated, but their genetic overlap is largely unknown. Here, we leveraged two large-scale genome-wide association studies performed to shed light on the shared genetics of rhythm (N=606,825) and dyslexia (N=1,138,870). Our results reveal an intricate shared genetic and neurobiological architecture, and lay groundwork for resolving longstanding debates about the potential co-evolution of human language and musical traits.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda