Nickel-Catalyzed Three-Component Alkylarylation of Alkenyl N-Heteroarenes.
Org Lett
; 25(46): 8344-8349, 2023 Nov 24.
Article
em En
| MEDLINE
| ID: mdl-37962415
A nickel-catalyzed three-component alkylarylation of alkenyl N-heteroarenes with α-bromocarboxylates and aryl boronic acids is reported. The protocol provides a new method to access a variety of N-heteroarene substituted diarylalkanes in moderate to good yields. It features mild reaction conditions, cheap nickel catalyst, readily available substrates, and broad substrate scope.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2023
Tipo de documento:
Article