No fitness cost entailed by type VI secretion system synthesis, assembly, contraction, or disassembly in enteroaggregative Escherichia coli.
J Bacteriol
; 205(12): e0035723, 2023 12 19.
Article
em En
| MEDLINE
| ID: mdl-37971272
ABSTRACT
IMPORTANCE Bacteria use weapons to deliver effectors into target cells. One of these weapons, the type VI secretion system (T6SS), assembles a contractile tail acting as a spring to propel a toxin-loaded needle. Due to its size and mechanism of action, the T6SS was intuitively thought to be energetically costly. Here, using a combination of mutants and growth measurements in liquid medium, on plates, and in competition experiments, we show that the T6SS does not entail a growth cost to enteroaggregative Escherichia coli.
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1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Escherichia coli
/
Sistemas de Secreção Tipo VI
Idioma:
En
Revista:
J Bacteriol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
França