Active tuberculosis patients have high systemic IgG levels and B-cell fingerprinting, characterized by a reduced capacity to produce IFN-Î³ or IL-10 as a response to <i>M.tb</i> antigens.

Flores-Gonzalez, Julio; Urbán-Solano, Alexia; Ramón-Luing, Lucero A; Cancino-Diaz, Juan Carlos; Contreras-Rodriguez, Araceli; Curiel-Quesada, Everardo; Hernández-Pando, Rogelio; Chavez-Galan, Leslie

Active tuberculosis patients have high systemic IgG levels and B-cell fingerprinting, characterized by a reduced capacity to produce IFN-Î³ or IL-10 as a response to M.tb antigens.

Flores-Gonzalez, Julio; Urbán-Solano, Alexia; Ramón-Luing, Lucero A; Cancino-Diaz, Juan Carlos; Contreras-Rodriguez, Araceli; Curiel-Quesada, Everardo; Hernández-Pando, Rogelio; Chavez-Galan, Leslie.

Afiliação

Flores-Gonzalez J; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Urbán-Solano A; Department of Microbiology, Laboratory of Immunomicrobiology, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Ramón-Luing LA; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Cancino-Diaz JC; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Contreras-Rodriguez A; Department of Microbiology, Laboratory of Immunomicrobiology, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Curiel-Quesada E; Department of Microbiology, Laboratory of Immunomicrobiology, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Hernández-Pando R; Department of Biochemistry, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Chavez-Galan L; Department of Pathology, Section of Experimental Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Front Immunol ; 14: 1263458, 2023.

Article em En | MEDLINE | ID: mdl-38022616

Assuntos

Tuberculose Latente; Mycobacterium tuberculosis; Tuberculose; Humanos; Interleucina-10; Interferon gama/metabolismo; Imunoglobulina G

Palavras-chave

B cells; IFN-g; IL-10; flow cytometry; humoral immunity; tuberculosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Tuberculose Latente / Mycobacterium tuberculosis Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México

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