Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group.

Li, Wenkui; Vazvaei-Smith, Faye; Dear, Gordon; Boer, Jason; Cuyckens, Filip; Fraier, Daniela; Liang, Yuexia; Lu, Ding; Mangus, Heidi; Moliner, Patricia; Pedersen, Mette Lund; Romeo, Andrea A; Spracklin, Douglas K; Wagner, David S; Winter, Serge; Xu, Xiaohui Sophia

Li, Wenkui; Vazvaei-Smith, Faye; Dear, Gordon; Boer, Jason; Cuyckens, Filip; Fraier, Daniela; Liang, Yuexia; Lu, Ding; Mangus, Heidi; Moliner, Patricia; Pedersen, Mette Lund; Romeo, Andrea A; Spracklin, Douglas K; Wagner, David S; Winter, Serge; Xu, Xiaohui Sophia.

Afiliação

Li W; Pharmacokinetic Sciences, Novartis Biomedical Research, East Hanover, New Jersey, USA.
Vazvaei-Smith F; Pharmacokinetics, Dynamics, Metabolism and Bioanalytics, Merck & Co., Inc., West Point, Pennsylvania, USA.
Dear G; Drug Metabolism and Pharmacokinetics, GSK, Ware, UK.
Boer J; Drug Metabolism and Pharmacokinetics, Incyte Corporation, Wilmington, Delaware, USA.
Cuyckens F; Drug Metabolism and Pharmacokinetics, Janssen R & D, Beerse, Belgium.
Fraier D; Pharmaceutical Sciences, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Liang Y; Pharmacokinetics, Dynamics, Metabolism and Bioanalytics, Merck & Co., Inc., West Point, Pennsylvania, USA.
Lu D; Drug Metabolism and Pharmacokinetics, Vertex Pharmaceuticals Inc., Boston, Massachusetts, USA.
Mangus H; Drug Metabolism and Pharmacokinetics, Agios Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
Moliner P; Enzymology and Metabolism, Department of Translational Medicine and Early Development, Sanofi, Montpellier, Occitanie, France.
Pedersen ML; DMPK, Research and Early Development, CVRM, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Romeo AA; Pharmaceutical Sciences, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Spracklin DK; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Inc., Groton, Connecticut, USA.
Wagner DS; Drug Metabolism and Disposition, AbbVie, North Chicago, Illinois, USA.
Winter S; Pharmacokinetic Sciences, Novartis Biomedical Research, Basel, Switzerland.
Xu XS; Clinical Bioanalysis, Translation Medicine, Daiichi Sankyo, Inc., Basking Ridge, New Jersey, USA.

Clin Pharmacol Ther ; 115(5): 939-953, 2024 May.

Article em En | MEDLINE | ID: mdl-38073140

Assuntos

Desenvolvimento de Medicamentos; Relatório de Pesquisa; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relatório de Pesquisa / Desenvolvimento de Medicamentos Limite: Humans Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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