Multi-taxon trends and the application of genotoxic biomarkers in the analysis of effluents from sewage treatment plant.

ABSTRACT

Sewage is a significant source of many contaminants, and the effectiveness of sewage treatment plants (STPs) is fundamental to ensure that the effluents produced by these plants have a minimal impact on aquatic environments and guarantee their long-term sustainability. The present study is based on a global scientometric survey of the published research on the application of genotoxicity biomarkers for the analysis of the effects of the contaminants found in the effluents and residues produced by STPs. The literature search focused on the Web of Science and Scopus databases. Research trends were investigated based on the year of publication of each study, the country in which it was developed, the type(s) of genotoxic assay applied, the model organism(s), the type of study (experimental or field study), the physicochemical parameters analyzed, and the principal findings of the genotoxic assays. A total of 134 papers, published between 1988 and April 2023, were selected for analysis. The studies were conducted in a total of 33 different countries, but primarily in Brazil, China, Germany. These studies employed 16 biomarkers to assess genotoxicity, of which, the micronucleus test was the most used. The studies reported on a number of genotoxic substances, such as pollutants, including pesticides, microplastics, metals, and drugs. The data produced by these studies provide important insights into the genotoxic effect of the xenobiotic agents found in STP effluents, which are capable of damaging the DNA of a range of different organisms.