The role of 18F-FDG PET/CT imaging in paediatric Langerhans disease: Case report.
Hell J Nucl Med
; 26(3): 215-218, 2023.
Article
em En
| MEDLINE
| ID: mdl-38149775
ABSTRACT
Langerhans cell histiocytosis (LCH) is a haematological disorder, affecting single or multiple organs, characterized by abnormal proliferation of Langerhans cells in children. Accurate tumour delineation (number of lesions, organs involved) is crucial for staging/re-staging, and follow-up (response to therapy). Conventional imaging techniques (computed tomography (CT), magnetic resonance imaging (MRI)) have been employed for initial diagnosis, staging and assessment of response to therapy focusing on the healing effect therapeutic protocols have on the disease. In this case report, whole-body positron emission tomography/computed tomography (PET/CT) was shown either to provide information on the metabolic activity of histiocytes, or identify lesions otherwise asymptomatic. It is clear that PET/CT, combining anatomic and metabolic information, provides data for accurate staging, therapeutic protocol selection and assessment of response to therapy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Histiocitose de Células de Langerhans
/
Fluordesoxiglucose F18
Limite:
Child
/
Humans
Idioma:
En
Revista:
Hell J Nucl Med
Assunto da revista:
MEDICINA NUCLEAR
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Grécia