The spectrum of post-myocardial infarction care: From acute ischemia to heart failure.
Prog Cardiovasc Dis
; 82: 15-25, 2024.
Article
em En
| MEDLINE
| ID: mdl-38242191
ABSTRACT
Heart failure (HF) is the leading cause of mortality in patients with acute myocardial infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI. HF post-MI develops due to complex inter-play between macrovascular obstruction, microvascular dysfunction, myocardial stunning and remodeling, inflammation, and neuro-hormonal activation. Cardiogenic shock is an extreme presentation of HF post-MI and is associated with a high mortality. Early revascularization is the only therapy shown to improve survival in patients with cardiogenic shock. Treatment of HF post-MI requires prompt recognition and timely introduction of guideline-directed therapies to improve mortality and morbidity. This article aims to provide an up-to-date review on the incidence and pathogenesis of HF post-MI, current strategies to prevent and treat onset of HF post-MI, promising therapeutic strategies, and knowledge gaps in the field.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Insuficiência Cardíaca
/
Infarto do Miocárdio
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Prog Cardiovasc Dis
/
Prog. cardiovasc. dis
/
Progress in cardiovascular diseases
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos