Lead exposure from honey: meta-analysis and risk assessment for the Arab region.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
; 41(3): 271-286, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38270899
ABSTRACT
The Codex Alimentarius Commission has adopted a maximum level for lead in honey (0.1 mg/kg). Despite representing a population of more than half a billion, exposure and risk assessments for lead specific to the Arab region are lacking. The aim of this work was to collect analytical data for lead in honey available in Arab countries and to assess the risk caused by exposure to lead from these samples for local consumers. A regional mean lead concentration in honey, obtained through a meta-analysis of 57 studies, was used in deterministic risk assessments for adults (nephrotoxicity and cardiovascular effects) and young children (developmental neurotoxicity). A regional pooled mean concentration of 0.12 mg/kg [95%CI 0.07-0.21] (0.13 mg/kg, if non-detects are considered at their highest possible value) was obtained. Margins of exposure of 363 [71-17182] and 865 [168-40909] were calculated for adults, and of 48 [9-2273] for children, indicating potential concern for the latter population subset. These values were produced using GEMS consumption data, and considering the same intake for both children and adults, potentially overestimating the risk for children. Nevertheless, food competent authorities should consider measures to reduce lead concentration in honey available for sale in the region to prevent trade constraints and to better protect vulnerable populations.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mel
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Adult
/
Child
/
Child, preschool
/
Humans
Idioma:
En
Revista:
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Canadá