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Critical care of severe bronchiolitis during shortage of ICU resources.
De Luca, Daniele; Pezza, Lucilla; Vivalda, Laura; Di Nardo, Matteo; Lepainteur, Margaux; Baraldi, Eugenio; Piastra, Marco; Ricciardi, Walter; Conti, Giorgio; Gualano, Maria Rosaria.
Afiliação
  • De Luca D; Division of Paediatrics and Neonatal Critical Care, "A. Béclère" Hospital, APHP-Paris Saclay University, Paris, France.
  • Pezza L; Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
  • Vivalda L; Division of Paediatrics and Neonatal Critical Care, "A. Béclère" Hospital, APHP-Paris Saclay University, Paris, France.
  • Di Nardo M; Division of Paediatrics and Neonatal Critical Care, "A. Béclère" Hospital, APHP-Paris Saclay University, Paris, France.
  • Lepainteur M; Paediatric Intensive Care Unit, "Bambino Gesù" Children's Hospital-IRCCS, Rome, Italy.
  • Baraldi E; Division of Bacteriology-Hygiene, "A. Béclère" Hospital, APHP-Paris Saclay University, Paris, France.
  • Piastra M; Neonatal Intensive Care Unit, Department of Woman's and Child's Health, University Hospital of Padova, Padua, Italy.
  • Ricciardi W; Respiratory Syncytial Virus Network (RESVINET) Foundation, Zeist, the Netherlands.
  • Conti G; Paediatric Intensive Care Unit, "A. Gemelli" University Hospital Foundation-IRCCS, Rome, Italy.
  • Gualano MR; Department of Biotechnological Sciences, Intensive and Perioperative Medicine, Catholic University of Sacred Heart, Rome, Italy.
EClinicalMedicine ; 69: 102450, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38333363
ABSTRACT
Large seasonal outbreaks of bronchiolitis put pressure on healthcare systems and particularly on intensive care units (ICUs). ICU admission is necessary to provide respiratory support to the severest cases, otherwise bronchiolitis can result in substantial mortality. ICU resources are often insufficient and there is scant evidence to guide the ICU clinical management. Most available studies do not cover the ICU-admitted cases and do not consider the associated public health issues. We review this topic through a multidisciplinary approach from both the clinical and public health perspectives, with an analysis based on pathophysiology and cost-effectiveness. We suggest ways to optimise respiratory care, minimise ICU stay, "protect" ICU beds and, whenever possible, make them available for other critically ill children. We also provide guidance on how to prepare ICUs to work under stressful conditions due to outbreaks and to reduce the risk of nosocomial cross-contamination, particularly in ICUs caring for high-risk children.

Funding:

None.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: EClinicalMedicine Ano de publicação: 2024 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: EClinicalMedicine Ano de publicação: 2024 Tipo de documento: Article País de afiliação: França