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Immune reconstitution inflammatory syndrome-associated lymphoma: A retrospective Brazilian cohort.
Vargas, Juliano Cordova; Cecyn, Karin Zattar; de Oliveira Marques, Mariana; Pereira, Juliana; Tobias Braga, Walter M; Hamerschlak, Nelson; Tabacof, Jacques; de Liz, Caina D; Abdo, André; Ferreira, Paulo Roberto Abrão; Colleoni, Gisele W Braga; Baiocchi, Otavio C G.
Afiliação
  • Vargas JC; Department of Clinical and Experimental Oncology Federal University of São Paulo São Paulo SP Brazil.
  • Cecyn KZ; Department of Hematology Américas Oncologia e Hematologia São Paulo SP Brazil.
  • de Oliveira Marques M; School of Medicine Centro Universitário São Camilo São Paulo SP Brazil.
  • Pereira J; Department of Clinical and Experimental Oncology Federal University of São Paulo São Paulo SP Brazil.
  • Tobias Braga WM; Department of Clinical and Experimental Oncology Federal University of São Paulo São Paulo SP Brazil.
  • Hamerschlak N; Department of Hematology Hospital Alemão Oswaldo Cruz São Paulo SP Brazil.
  • Tabacof J; Department of Clinical and Hematology São Paulo State Cancer Institute University of São Paulo São Paulo SP Brazil.
  • de Liz CD; Department of Hematology Emílio Ribas Institute of Infectious Diseases São Paulo SP Brazil.
  • Abdo A; Department of Hematology Américas Oncologia e Hematologia São Paulo SP Brazil.
  • Ferreira PRA; Department of Hematology Hospital Israelita Albert Einstein São Paulo SP Brazil.
  • Colleoni GWB; Centro Paulista de Oncologia São Paulo SP Brazil.
  • Baiocchi OCG; Department of Hematology Hospital Sírio Libanês São Paulo SP Brazil.
EJHaem ; 5(1): 147-152, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38406522
ABSTRACT
After initiating combined antiretroviral therapy (cART), individuals with human immunodeficiency virus (HIV) may develop Hodgkin/non-Hodgkin lymphoma due to immune reconstitution inflammatory syndrome (IRIS). This retrospective cohort study evaluated the incidence, clinical features and prognosis of IRIS-associated lymphomas in Brazilian patients. Incidence in 2000-2019 was 9.8% (27/276 patients with HIV and lymphoma; viral load drop >1 log). Time between HIV diagnosis and cART initiation was <1 year in 70.3% of cases. Time between cART initiation and lymphoma diagnosis was <3 months in 11 cases and 3-6 months in 16 cases. Overall and progression-free survival rates were similar between cases of non-IRIS-associated lymphoma and IRIS-associated lymphoma.
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Texto completo: 1 Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: EJHaem Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: EJHaem Ano de publicação: 2024 Tipo de documento: Article