Role of PD-1 and immune cells in HSV infection and latency.
Future Microbiol
; 19: 349-354, 2024 03.
Article
em En
| MEDLINE
| ID: mdl-38411117
ABSTRACT
A large proportion of the world's population is infected with HSV-1. Antiviral CD8+ T cells and CD8α+ dendritic cells are closely related to HSV-1 infection and latency. Latency-associated transcript of HSV-1 and PD-1 are involved in the regulation of latency and reactivation of HSV-1. Here, the role of latency-associated transcript, PD-1, CD8+ T cells and CD8α+ dendritic cells in HSV-1 infection, the inter-relationships between them and how these interactions lead to latency are discussed, possibly providing new ideas for the treatment of HSV-1 infection.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Herpesvirus Humano 1
/
Herpes Simples
Limite:
Humans
Idioma:
En
Revista:
Future Microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China