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Dietary therapy of the herbal porridge improves the symptoms of functional dyspepsia: A randomized, double-blind, placebo-controlled, clinical trial.
Wang, Xin; Liu, Meng-Ao; He, Jia; Zhao, Wen-Zhi; Wang, Yi-Xuan; Yang, Liu-Qing; Wang, Tian-Yuan; Shi, Han-Ping; Rao, Ben-Qiang.
Afiliação
  • Wang X; Departments of General Surgery, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • Liu MA; Center of Nutrition and Metabolism of Cancer, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • He J; Key Laboratory of Cancer FSMP for State Market Regulation Beijing China.
  • Zhao WZ; Beijing International Science and Technology Cooperation Base for Cancer Metabolism and Nutrition Beijing China.
  • Wang YX; Departments of General Surgery, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • Yang LQ; Center of Nutrition and Metabolism of Cancer, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • Wang TY; Departments of Critical Care Medicine, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • Shi HP; Departments of General Surgery, Beijing Shijitan Hospital Capital Medical University Beijing China.
  • Rao BQ; Center of Nutrition and Metabolism of Cancer, Beijing Shijitan Hospital Capital Medical University Beijing China.
Food Sci Nutr ; 12(3): 2104-2114, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38455174
ABSTRACT
This study (ISRCTN17174559) aimed to explore the efficacy and safety of a kind of herbal porridge (Hou Gu Mi Xi) on the clinical symptoms of functional dyspepsia (FD). This was a single-center, single-dose, prospective, double-blind, randomized controlled trial involving 64 participants with FD (35 cases and 29 controls) for 2 months of intervention and 1 month of follow-up. The 7-point Global Overall Symptom Scale (GOSS), 36-Item Short Form Survey (SF-36), and other indicators were assessed at baseline (day 0), at days 15, 30, and 60 of treatment, and at follow-up 1 month after the end of the intervention. Many participants with FD achieved remission of their epigastric symptoms at follow-up on the 90th day after treatment with herbal porridge compared to the placebo group (45.71% vs. 20.69%, p = .036). Furthermore, herbal porridge appeared to be effective in improving the quality of life of participants with FD, which was reflected in the rising SF-36 scores for physical role, bodily pain, emotional role, and mental health. Although adverse events were reported, there was no overall difference in the number of adverse events between the two groups (p = .578). Herbal porridge is another effective and safe method for improving the symptoms and quality of life in patients with FD.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Food Sci Nutr Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Food Sci Nutr Ano de publicação: 2024 Tipo de documento: Article