Association between lymph node ratio and survival outcomes in patients with oral squamous cell carcinoma.
J Stomatol Oral Maxillofac Surg
; 125(3S): 101816, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38458548
ABSTRACT
BACKGROUND:
Recent reports have shown that the Lymph node ratio (LNR) is useful for predicting the prognosis in some cancers, however there are few reports on the usefulness of LNR in predicting the prognosis of oral squamous cell carcinoma (OSCC). The predictive value of LNR for prognosis of OSCC was investigated. MATERIALS ANDMETHODS:
The study included 152 patients with OSCC and histologically confirmed cervical lymph node metastasis who underwent neck dissection. We analyzed the relationship between LNR and overall survival (OS) and recurrence-free survival (RFS) retrospectively in these cases, with the relationship between prognosis and clinicopathological findings also examined.RESULTS:
Using a receiver operating characteristics curve, the LNR cutoff value was set at 0.095, categorizing 64 and 88 cases into high LNR (≥ 0.095) and low LNR (< 0.095) groups, respectively. Regarding OS and RFS, the prognosis was significantly worse in the high LNR group compared with the low LNR group. In multivariate analysis, sex, postoperative nodal stage, and LNR merged as independent prognostic factors.CONCLUSION:
This study's findings suggest that LNR may represent a prognostic indicator in OSCC with cervical lymph node metastasis.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Esvaziamento Cervical
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Neoplasias Bucais
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Carcinoma de Células Escamosas
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Razão entre Linfonodos
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Metástase Linfática
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Stomatol Oral Maxillofac Surg
Ano de publicação:
2024
Tipo de documento:
Article