An inside job: New roles for ApoE at the lipid droplet.

Feringa, Femke M; van der Kant, Rik

Feringa, Femke M; van der Kant, Rik.

Afiliação

Feringa FM; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
van der Kant R; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

J Cell Biol ; 223(4)2024 Apr 01.

Article em En | MEDLINE | ID: mdl-38466168

ABSTRACT

ABSTRACT

The secreted ApoE protein is a major regulator of lipid transport between brain cells. In this issue, Windham et al. (https//doi.org/10.1083/jcb.202305003) uncover a novel intracellular role for ApoE at the lipid droplet surface, where it regulates lipid droplet size and composition.

Assuntos

Apolipoproteínas E; Gotículas Lipídicas; Apolipoproteínas E/metabolismo; Transporte Biológico; Gotículas Lipídicas/metabolismo; Humanos; Animais

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Gotículas Lipídicas Limite: Animals / Humans Idioma: En Revista: J Cell Biol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda

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