Your browser doesn't support javascript.
loading
Synthesis of easily-modified and useful dibenzo-[b,d]azepines by palladium(II)-catalyzed cyclization/addition with a green solvent.
Cheng, Hua; Liu, Rongqi; Fang, Shengyang; Li, Zixiang; Zhang, Denggao; Zhang, Xi; Chen, Wenfei; Chen, Huixin; Kang, Leyi; Wang, Juan; Xu, Yulong; Song, Shaoli; Shao, Liming.
Afiliação
  • Cheng H; School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China. limingshao@fudan.edu.cn.
  • Liu R; China Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270, Dong'an Road, Xuhui District, Shanghai 200032, China. shaoli-song@163.com.
  • Fang S; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. yulong.xu@mgh.harvard.edu.
  • Li Z; School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China. limingshao@fudan.edu.cn.
  • Zhang D; School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China. limingshao@fudan.edu.cn.
  • Zhang X; School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China. limingshao@fudan.edu.cn.
  • Chen W; School of Pharmacy, Fudan University, 826 Zhangheng Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China. limingshao@fudan.edu.cn.
  • Chen H; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. yulong.xu@mgh.harvard.edu.
  • Kang L; School of Medicine, Shanghai University, Shanghai 200444, China. juanw@shu.edu.cn.
  • Wang J; School of Medicine, Shanghai University, Shanghai 200444, China. juanw@shu.edu.cn.
  • Xu Y; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. yulong.xu@mgh.harvard.edu.
  • Song S; School of Medicine, Shanghai University, Shanghai 200444, China. juanw@shu.edu.cn.
  • Shao L; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. yulong.xu@mgh.harvard.edu.
Chem Commun (Camb) ; 60(26): 3587-3590, 2024 Mar 26.
Article em En | MEDLINE | ID: mdl-38470314
ABSTRACT
A novel strategy in which palladium(II)-catalyzed tandem cyclization is used to obtain N-heterocyclic architectures containing a seven-membered ring has been developed and used to synthesize a series of derivatives. The reaction uses an eco-friendly mixed solvent (water EtOH = 2 1) instead of DMSO and maintains a high yield (91%). Its potential application value and reaction mechanism have also been explored.
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China