IL-4-ever young: Type 2 cytokine signaling in macrophages slows aging.
Immunity
; 57(3): 403-406, 2024 Mar 12.
Article
em En
| MEDLINE
| ID: mdl-38479355
ABSTRACT
Macrophages activated via the IL-4 receptor possess non-immune functions that support tissue homeostasis, but their specific role in aging is unknown. In this issue of Immunity, Zhou et al. show that IL-4 extends lifespan by inducing DNA repair pathways that protect macrophages from cellular senescence.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Interleucina-4
/
Macrófagos
Idioma:
En
Revista:
Immunity
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article